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   - December 1, 2008
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 Presentation

"Microalbuminuria and Kidney Disease In Type 2 Diabetes"

Dr. Steven Soroka (biography)
English - 2002-11-23 - 28 minutes
(46 slides)

Summary :
Here we will get a nephrology perspective on type 2 diabetes. Type 2 diabetes and chronic kidney disease are both common, but microalbuminuria (MAU) is more closely correlated with CVD than is kidney disease. Two important questions we have been asking ourselves are: What are the modifiable risk factors for kidney disease? And, What is the most cost effective way of treating kidney disease and preventing end stage kidney failure? Treatment of hypertension postpones renal insufficiency in diabetic nephropathy, and intensive blood pressure control has been shown to be cost effective. Studies indicate RAAS blockade as an appropriate treatment for the diabetic nephropathy patient. Both ACEs and ARBs can not only decrease the onset of new diabetes, but also decrease the albumin excretion rate, decrease cardiovascular events; and ARBs have shown to decrease end stage renal disease events (ESRD). Furthermore, studies have shown routine RAAS inhibition in all diabetics to be cost effective as well.

Learning objectives :
The participant will get a nephrology perspective on the delay of onset and treatment of diabetic nephropathy:

- Diabetes and chronic kidney disease are common
- Early, aggressive treatment is needed
- Blood pressure control is essential and cost effective
- RAAS blockade confers additional cardio renal protection


Bibliographic references :
Deira J, Diaz H, Grande J. 2003. Complete blockade of the Renin-Angiotensin system in patients with advanced diabetic nephropathy. Diabetes Care 2003 May;26(5):1635-6

Jungmann E. 2003. Prevention and treatment of diabetic nephropathy in older patients. Drugs Aging 2003;20(6):419-35
http://www.ncbi.nlm.nih.gov/


   


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