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   - December 1, 2008
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 Presentation

"Obesity Management Part III - Pharmacotherapy"

Dr. Trisha O'Moore-Sullivan (biography)
English - 2005-09-11 - 15 minutes
(14 slides)

Summary :
Pharmacotherapies for obesity are currently few in number and costly. They might possibly be more cost-effective if used for weight maintenance, and should always be seen as adjuncts to calorie restriction and lifestyle therapy, says Dr. O'Moore-Sullivan.

Commonly used agents are orlistat, which inhibits the absorption of dietary fat, and sibutramine, a noradrenaline-serotonin reuptake inhibitor. The cannabinoid receptor 1 antagonists are a new class of agents, and one of these, rimonabant, was recently reported to cause significant weight loss and to improve cardiovascular risk factors (1).

Copyright © 2005 E-MedHosting.com Inc.

Learning objectives :
After viewing this presentation the participant will be able to discuss:

- Targets for pharmacotherapy of obesity
- Commonly used agents, their mechanisms of action and effects

Bibliographic references :
1. ProfLuc F Van Gaal, Aila M Rissanen, André J Scheen, Olivier Ziegler, Stephan Rössner and for the RIO-Europe Study Group
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study The Lancet, Volume 365, Issue 9468, 16 April 2005-22 April 2005, Pages 1389-1397.

   


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