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- December 1, 2008 |
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| Presentation |
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"Origin and Development of the Metabolic Syndrome"Prof. Gaetano Crepaldi (biography)
English - 2005-04-14 - 32 minutes
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 | (43 slides) |
Summary :
The metabolic syndrome, as a conceptual entity, is a relatively young one. However, the first descriptions of the syndrome and its associated pathology reach as far back as the 17th century. Prof. Gaetano Crepaldi of the University of Padua leads us through the history of the metabolic syndrome, from the first observations of Turp and Morgagni to the accelerated understanding of this “peculiar syndrome” in the last 40 years.
We are brought to the present day by Prof. Crepaldi, as he contrasts the competing definitions of the metabolic syndrome and introduces the new emerging consensus, highlighting important recent scientific achievements in the field along the way.
Of particular interest, Prof. Crepaldi reviews some of the key findings of the Italian Longitudinal Study on Aging (ILSA, in press) and the concept of LDL buoyancy and its importance for atherosclerotic risk.
Copyright © 2005 E-MedHosting.com Inc
Learning objectives :
After viewing this presentation, participants will be able to discuss:
• The history of the metabolic syndrome
• The different definitions of the metabolic syndrome
• The new consensus on the definitions of the components of the metabolic syndrome
• Recent scientific achievements in the study of the components of the metabolic syndrome
• The results of the Italian Longitudinal Study of Aging (ILSA)
• Future challenges in the study the metabolic syndrome
Bibliographic references :
P. Avogaro, G. Crepaldi, G. Enzi, A. Tiengo. Association of hyperlipemia, diabetes mellitus and mild obesity. Acta Diabetologica Latina, Vol IV, 1967
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) JAMA 2001; 285: 2486-2497.
Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002 Jan 16;287(3):356-9.
Superko HR. Beyond LDL cholesterol reduction. Circulation. 1996 Nov 15;94(10):2351-4.
Austin MA, Edwards KL. Small, dense low density lipoproteins, the insulin resistance syndrome and noninsulin-dependent diabetes. Curr Opin Lipidol. 1996 Jun;7(3):167-71.
Thompson SG, Kienast J, Pyke SD, Haverkate F, van de Loo JC. Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group. N Engl J Med. 1995 Mar 9;332(10):635-41.
Faggin E, Zambon A, Puato M, Deeb SS, Bertocco S, Sartore S, Crepaldi G, Pessina AC, Pauletto P. Association between the --514 C-->T polymorphism of the hepatic lipase gene promoter and unstable carotid plaque in patients with severe carotid artery stenosis. J Am Coll Cardiol. 2002 Sep 18;40(6):1059-66.
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