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- December 1, 2008 |
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Welcome to the #1 online source of information for Diabetes Specialists! An international online community of more than 10,000 Diabetes Specialists.
CME on Diabetes is a website built to transmit top-level CME conferences given by international experts in endocrinology, insulin resistance, prediabetes, metabolic syndrome and type 2 diabetes. More than 2.6 million slides have been viewed since the website launch. Thank you for your continued support and commitment!
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"Primary Prevention of Type 2 Diabetes - A Matter of Maintaining the New Lifestyle"Dr. Bernt Lindahl (biography)
English - 2005-04-15 - 16 minutes
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Summary :
Object: To study short- and long-term effects of an intensive lifestyle change programme.
Method: Subjects with IGT and obesity (BMI>27) were randomised to two different intervention programmes based on low-fat, high-fibre diet and regular physical exercise. The intensive group (n=100) participated in a one month learning and training session using behavioural modification techniques and conducted in a full-board wellness centre. The usual care group (n=94) was randomised to a one-hour counselling session. Follow-up was done after 1, 3 and 5 years.
Results: At 1-year follow-up, in the intensive versus the usual care group there was a 70 % reduction in worsening to type 2 diabetes (T2DM). Body mass index, waist circumference, blood pressure, fasting proinsulin, leptin, PAI-1 activity, tPA-antigen and LDL-cholesterol were all significantly lowered in the intensive compared to the usual care group. Furthermore, healthy eating habits had improved and physical activity along with HDL-cholesterol had increased. At 5-year follow-up, most of the attained differences between the groups in risk factors as well as in diabetes incidence had disappeared. This was mainly due to adherence problems. However, fasting proinsulin was still lower and HDL-cholesterol higher in the intensive group.
Conclusions: Lifestyle change induces a multitude of beneficial metabolic effects that may protect against cardiovascular disease and T2DM. However, these metabolic effects only persist as long as the lifestyle regimen is maintained.
Learning objectives :
After viewing this presentation, participants will be able to discuss:
- Compliance-oriented and empowerment-oriented approaches to behaviour modification
- The design of the GT-VIP Study
- The short-term effects of an intensive behavioural intervention in the GT-VIP
- The long-term effects of an intensive behavioural intervention in the GT-VIP
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