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- December 1, 2008 |
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CME on Diabetes is a website built to transmit top-level CME conferences given by international experts in endocrinology, insulin resistance, prediabetes, metabolic syndrome and type 2 diabetes. More than 2.6 million slides have been viewed since the website launch. Thank you for your continued support and commitment!
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"Review of epidemiological data for thiazolidinediones and cardiovascular outcomes" A.Prof. Bruce Neal (biography)
English - 2007-11-10 - 39 minutes
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Summary :
In this presentation A.Prof. Neal addresses the questions of whether thiazolidinediones have an effect, either beneficial or detrimental on cardiovascular outcomes, and whether there are differences between agents in this drug class.
From a methodological perspective, what constitutes evidence about the detection of treatment effects? Precision and validity are needed, and to have these together requires a large-scale randomised trial or a quantitative overview of multiple randomised trials.
A.Prof. Neal discusses the conclusions of different overviews on TZD-associated risk and limitations of these analyses.
Copyright © 2008 E-MedHosting.com Inc.
Learning objectives :
After viewing this presentation the participant will be able to discuss:
Data relating to the following questions and the current conclusions that can be made:
- Do TZDs have an effect on the occurrence of cardiovascular events (either beneficial or harmful)?
- Are there differences between agents within the TZD class?
Bibliographic references :
Lago RM, Singh PP, Nesto RW.Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials Lancet. 2007 Sep 29;370(9593):1129-36.
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