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   - November 21, 2008
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 Presentation

"What is the increasing evidence that supports TZDs and their extraglycemic benefits?"

Dr. Julio Rosenstock (biography)
English - 2004-06-04 - 10 minutes
(3 slides)

Summary :
Thiazolidinediones have been shown to cause improvements in dyslipidemia, microalbuminuria, blood pressure, vascular smooth muscle cell prolferation/migration in the arterial wall, and Plasminogen Activator Inhibitor-1 (PAI-1) and C-reactive protein (CRP) levels.

More information is available about C-Reactive Protein.

Copyright © 2004 E-MedHosting.com Inc.

Learning objectives :
After viewing these slides the participant will be able to discuss:

- The improvement of cardiovascular risk factors with thiazolidinediones
- Inflammation as a link between diabetes and atherosclerosis

Bibliographic references :
Neelima V. Chu, MD, Alice P. S. Kong, MRCP, Dennis D. Kim, MD, Debra Armstrong, RN, Sunita Baxi, MD, Reena Deutsch, PHD, Michael Caulfield, PHD, Sunder R. Mudaliar, MD, MRCP, Richard Reitz, MD, Robert R. Henry, MD, FRCP and Peter D. Reaven, MD. Differential Effects of Metformin and Troglitazone on Cardiovascular Risk Factors in Patients With Type 2 Diabetes Diabetes Care.2002;25:542-549.

Peter Libby, MD; Paul M. Ridker, MD; Attilio Maseri, MD.Inflammation and Atherosclerosis Circulation. 2002;105:1135.

Suwattee, Pitiporn M.D.; DeSouza, Cyrus M.D.; Asnani, Sunil M.D.; Gilling, Lucia M.D.; Fonseca, Vivian A. M.D.Cardiovascular Effects of Thiazolidinediones. The Endocrinologist 2002;12(2):126-134.

   


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